Frank Charles Mann

15th APS President (1935-1937)
Frank Charles Mann
(1887-1962)

During Frank C. Mann's term as president, APS was preoccupied with preparations for its Semicentennial Celebration to take place at the annual Federation meeting to be held in Baltimore in 1938. Born on the family farm in Indiana, Mann received his B.A. (1911), M.D. (1913), and M.A. (1914) degrees from Indiana University. His early work in surgical shock while instructor of experimental surgery at the University of Indiana led to his appointment in 1914 as Director of Experimental Medicine and Pathological Anatomy at the Mayo Clinic. In 1915, when the Mayo Foundation was created as part of the Graduate School of the University of Minnesota, Mann became assistant professor of experimental surgery. He became associate professor in 1918 and held the rank of professor from 1921 to his retirement in 1952. All together, several hundred graduate students, mostly fellows of the Mayo Foundation, worked in his laboratory.

A prolific investigator, Mann was noted for his exceptional surgical skill. He was a pioneer in the experimental removal of the liver. By using hepatectomized animals, he was able to establish the crucial role of the liver in supplying glucose to the body and in the formation of urea. He also contributed to the pathogenesis of diseases of the digestive system, including peptic ulcer, pancreatitis, and cholecystitis. During both World War I and World War II, he was associated with the National Research Council's efforts to study traumatic shock.

Before his election to the presidency in 1935, Mann served as secretary of the Society from 1932 to 1935. He was a member of the Board of Publication Trustees from 1946 to 1951 and also served as chairman of the board of Annual Review of Physiology for many years during the period that the Society exercised joint control of its publication. In his prefatory chapter for Annual Review of Physiology in 1955, Mann recalled:
"I received the honor of membership in the American Physiological Society in 1916, and gave my first paper before the society at the Minneapolis and Rochester meeting in 1917. I found so much inspiration, pleasure, and value in these meetings that I attended every one for 35 years."

Selected Publications

1. Anonymous. Frank Charles Mann, 1887-1962. Physiologist 15: 1-3, 1972.

2. Essex, H. E. Dr. Frank C. Mann. Physiologist 6: 66-69, 1963.

3. Howell, W. H., and C. W. Greene. History of the American Physiological Society Semicentennial, 1887-1937. Baltimore, MD: Am. Physiol. Soc., 1938, p. 160-161.

4. Mann, F. C. To the physiologically inclined. Annu. Rev. Physiol. 17: 1-16, 1955.

5. Visscher, M. B. Frank Charles Mann, September 11, 1887-September 30, 1962. Biogr. Mem. Natl. Acad. Sci. 38: 161-204, 1965.