Stanley G. Schultz

65th APS President (1992-1993)
Stanley G. Schultz
(b. 1931)

Stanley G. Schultz, professor and chairman of the Department of Physiology and Cell Biology at the University of Texas Medical School in Houston, was installed as the 65th President of the American Physiological Society at the close of the Society's Spring Meeting in Anaheim, CA.

During the 26 years he has been a member of the APS, Schultz has served as editor of the American Journal of Physiology: Gastrointestinal and Liver Physiology, Physiological Reviews, the second edition of the Handbook of Physiology: Gastrointestinal System, and is currently an associate editor of News in Physiological Sciences. He also served on the recent Long-Range Planning Committee chaired by Ernst Knobil, whose report entitled "What is Past is Prologue" was published in the December 1990 issue of The Physiologist. Schultz was elected to the Council in 1989 and as president-elect in 1991.

Schultz grew up in New York City. He received his baccalaureate, summa cum laude, from Columbia University in 1952 and his MD degree from New York University four years later. After serving an internship and residency in internal medicine, he became an NIH postdoctoral fellow in cardiology and developed an interest that prompted him to learn more about membranes and electrophysiology, and in 1959 he joined the Biophysical Laboratories of the Harvard Medical School sponsored by a National Academy of Sciences/National Research Council Fellowship in Academic Medicine.

In 1962 Schultz was inducted into the Air Force as a Captain in the Medical Corps and was stationed at the Brooks Aerospace School of Medicine in San Antonio, Texas, where his primary responsibilities included teaching radiation biology, monitoring Air Force research contracts, and carrying out research dealing with the biological effects of radiation. It was here that he launched his research interest in epithelial transport and, together with Ralph Zalusky, demonstrated, for the first time, sodium-coupled sugar and amino acid absorption by small intestine. These and subsequent findings established the "sodium-gradient" hypothesis and provided the rationale for the later development of oral rehydration therapy.

Schultz rejoined the Biophysical Laboratories in 1964 as an Established Investigator of the American Heart Association and was promoted through the ranks of instructor and associate in biophysics. In 1967 he joined the Department of Physiology at the University of Pittsburgh School of Medicine as an associate professor and was promoted to the rank of professor three years later. He assumed his present position in 1979.

Schultz is widely recognized for his contributions to the understanding of epithelial ion transport. In addition to his work on sodium-coupled nonelectrolyte absorption, he was one of the first to recognize the roles of paracellular pathways in epithelia. In 1979 he and his former students Raymond Frizzell and Michael Field suggested a cellular model for chloride secretion by epithelial cells that is now widely accepted. More recently he advance the notions of "homocellular regulation" of composition and volume and the "pump-leak" parallelism in epithelial cells--subjects that are currently under investigation in a number of laboratories.

Schultz has served as a member and chairman of the Physiology Test Committee of the National Board of Medical Examiners and president of the Association of Chairmen of Departments of Physiology. His awards include the Hoffman-LaRoche Prize for Outstanding Contributions to Gastroenterology and elections to the Association of American Physicians, to Honorary Membership in the American Gynecological and Obstetrical Society, and as Overseas Fellow of Churchill College, Cambridge University. In 1981, Schultz was listed among the 1,000 most-cited contemporary scientists and the 35 most-cited contemporary physiologists by the Institute for Scientific Information.