• Episode 5

    Research on Heart Hormones and Cancer

    In this episode of Life Lines, we talk to David Vesely, a professor at the University of South Florida and chief of endocrinology, diabetes and metabolism at the James A. Haley Veterans Hospital in Tampa. He talks about his research investigating the use of heart hormones as a treatment for cancer. He has just finished trials with mice and hopes to begin human trials this year.
  • Episode 6

    The Mystery of Serotonin and Hypertension

    This episode features an interview with Michigan State University Professor Stephanie W. Watts, who has been investigating whether serotonin plays a role in high blood pressure. She received the 2008 Henry Pickering Bowditch Memorial Award for early-career achievement. It is the American Physiological Society's second-highest award.
  • Episode 17

    Environmental Cardiology

    This episode covers several areas under one topic. Accumulating evidence indicates that an increase in particulate air pollution is associated with an increase in heart attacks and deaths. In this episode, we talk to Aruni Bhatnagar of the University of Louisville and Robert Brook of the University of Michigan about research in the relatively new field of environmental cardiology. This field examines the relationship between air pollution and heart disease. (Begins at 02:58)
  • Episode 21

    Blood Pressure and the Brain

    In this episode, we talk to Francois Abboud of the Carver College of Medicine at the University of Iowa, whose research identified a new sensor. We’ll talk to him about his new research looking at genes that regulate ion channels, microscopic gates that move chemicals in and out of cells and that play a role in the signaling between the brain and the blood vessels. In experiments with animals, Dr. Abboud and his colleagues deleted one specific ion channel and found that the animals developed high blood pressure.
  • Episode 26

    Invention and Impact of Ultrasound

    Dean Franklin developed the first instruments to measure blood flow and the changes in diameter of the pulsating heart in conscious animals. He also pioneered the use of radio waves to measure heart and blood vessel function without wiring the body to the instrument. Dusty Sarazan, a former student of Franklin's, explains how these inventions led to the noninvasive cardiovascular monitoring instruments we have today. (Note: We misspoke when we said that physiologists made an important discovery after a giraffe frightened an instrumented baboon. In fact, a leopard had frightened the baboon.)
  • Episode 28

    'Tis the Season That's Hard on Your Heart

    Heart attacks peak during the winter months, and cold weather has been thought to be the primary culprit. However, cardiologist Robert Kloner of the Keck School of Medicine and Good Samaritan Hospital found that heart attack deaths peak on Christmas and New Year's in the mild climate of Los Angeles County. Could it be that the weather is not the most important factor behind the seasonal increase in heart attacks?
  • Episode 29


    From the cutting room floor, here are some of the outtakes about physiology that we thought were just too interesting not to use. In segment one, Dusty Sarazan describes one way that physiological research helped advance cardiac surgery and also how research led to the development of the modern treadmill.